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Side-Chain Pruning Has Limited Impact on Substrate Preference in a Promiscuous Enzyme
[Image: see text] Detoxifying enzymes such as flavin-containing monooxygenases deal with a huge array of highly diverse xenobiotics and toxic compounds. In addition to being of high physiological relevance, these drug-metabolizing enzymes are useful catalysts for synthetic chemistry. Despite the wea...
Autores principales: | Fürst, Maximilian J. L. J., Romero, Elvira, Gómez Castellanos, J. Rúben, Fraaije, Marco W., Mattevi, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345240/ https://www.ncbi.nlm.nih.gov/pubmed/30687578 http://dx.doi.org/10.1021/acscatal.8b03793 |
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