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Reduction in IGF1 mRNA in the Human Subependymal Zone During Aging

The cell proliferation marker, Ki67 and the immature neuron marker, doublecortin are both expressed in the major human neurogenic niche, the subependymal zone (SEZ), but expression progressively decreases across the adult lifespan (PMID: 27932973). In contrast, transcript levels of several mitogens...

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Detalles Bibliográficos
Autores principales: Weissleder, Christin, Barry, Guy, Fung, Samantha J., Wong, Matthew W., Double, Kay L., Webster, Maree J., Weickert, Cynthia Shannon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345338/
https://www.ncbi.nlm.nih.gov/pubmed/30705779
http://dx.doi.org/10.14336/AD.2018.0317