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LMNA-mutated Rabbits: A Model of Premature Aging Syndrome with Muscular Dystrophy and Dilated Cardiomyopathy

Premature aging syndromes are rare genetic disorders mimicking clinical and molecular features of aging. Products of the LMNA gene, primarily lamin A and C, are major components of the nuclear lamina. A recently identified group of premature aging syndromes was related to mutations of the LMNA gene....

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Detalles Bibliográficos
Autores principales: Sui, Tingting, Liu, Di, Liu, Tingjun, Deng, Jichao, Chen, Mao, Xu, Yuanyuan, Song, Yuning, Ouyang, Hongsheng, Lai, Liangxue, Li, Zhanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345340/
https://www.ncbi.nlm.nih.gov/pubmed/30705772
http://dx.doi.org/10.14336/AD.2018.0209