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Microtubule-Based Control of Motor-Clutch System Mechanics in Glioma Cell Migration
Microtubule-targeting agents (MTAs) are widely used chemotherapy drugs capable of disrupting microtubule-dependent cellular functions, such as division and migration. We show that two clinically approved MTAs, paclitaxel and vinblastine, each suppress stiffness-sensitive migration and polarization c...
Autores principales: | Prahl, Louis S., Bangasser, Patrick F., Stopfer, Lauren E., Hemmat, Mahya, White, Forest M., Rosenfeld, Steven S., Odde, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345402/ https://www.ncbi.nlm.nih.gov/pubmed/30485822 http://dx.doi.org/10.1016/j.celrep.2018.10.101 |
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