Graft-implanted, enzyme responsive, tacrolimus-eluting hydrogel enables long-term survival of orthotopic porcine limb vascularized composite allografts: A proof of concept study

BACKGROUND: Currently, patients receiving vascularized composite allotransplantation (VCA) grafts must take long-term systemic immunosuppressive therapy to prevent immunologic rejection. The morbidity and mortality associated with these medications is the single greatest barrier to more patients bei...

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Detalles Bibliográficos
Autores principales: Fries, C. Anton, Lawson, Shari D., Wang, Lin C., Slaughter, Kai V., Vemula, Praveen K., Dhayani, Ashish, Joshi, Nitin, Karp, Jeffrey M., Rickard, Rory F., Gorantla, Vijay S., Davis, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345449/
https://www.ncbi.nlm.nih.gov/pubmed/30677062
http://dx.doi.org/10.1371/journal.pone.0210914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345449/
https://www.ncbi.nlm.nih.gov/pubmed/30677062
http://dx.doi.org/10.1371/journal.pone.0210914

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