Cargando…

Graft-implanted, enzyme responsive, tacrolimus-eluting hydrogel enables long-term survival of orthotopic porcine limb vascularized composite allografts: A proof of concept study

BACKGROUND: Currently, patients receiving vascularized composite allotransplantation (VCA) grafts must take long-term systemic immunosuppressive therapy to prevent immunologic rejection. The morbidity and mortality associated with these medications is the single greatest barrier to more patients bei...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fries, C. Anton, Lawson, Shari D., Wang, Lin C., Slaughter, Kai V., Vemula, Praveen K., Dhayani, Ashish, Joshi, Nitin, Karp, Jeffrey M., Rickard, Rory F., Gorantla, Vijay S., Davis, Michael R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345449/ https://www.ncbi.nlm.nih.gov/pubmed/30677062 http://dx.doi.org/10.1371/journal.pone.0210914

Ejemplares similares

Local release of tacrolimus from hydrogel-based drug delivery system is controlled by inflammatory enzymes in vivo and can be monitored non-invasively using in vivo imaging
por: Dzhonova, Dzhuliya, et al.
Publicado: (2018)

Chemical fuel-driven living and transient supramolecular polymerization
por: Jain, Ankit, et al.
Publicado: (2019)

Medication eluting devices for the field of OBGYN (MEDOBGYN): 3D printed biodegradable hormone eluting constructs, a proof of concept study
por: Tappa, Karthik, et al.
Publicado: (2017)

Everolimus-eluting stents versus sirolimus-eluting stents in patients with cardiac allograft vasculopathy
por: Hawranek, Michał, et al.
Publicado: (2021)

Tacrolimus-Associated Dilated Cardiomyopathy in Adult Patient After Orthotopic Liver Transplant
por: McLeod, Jennifer, et al.
Publicado: (2017)

SKELETAL MUSCLE AS A PRIVILEGED SITE FOR ORTHOTOPIC SKIN ALLOGRAFTS
por: Barker, Clyde F., et al.
Publicado: (1973)

Far-Infrared Therapy Decreases Orthotopic Allograft Transplantation Vasculopathy
por: Lin, Yi-Wen, et al.
Publicado: (2022)

Tacrolimus-Induced Thrombotic Microangiopathy After Orthotopic Heart Transplant: A Case Report
por: Gill, Rajwinder, et al.
Publicado: (2022)

Development and effects of tacrolimus-loaded nanoparticles on the inhibition of corneal allograft rejection
por: Wu, Qianni, et al.
Publicado: (2019)

α1-Antitrypsin attenuates acute rejection of orthotopic murine lung allografts
por: Nakagiri, Tomoyuki, et al.
Publicado: (2021)

The Role of Cyclosporine and Mycophenolate in an Orthotopic Porcine-to-Rat Corneal Xenotransplantation
por: Lee, Hyeon Il, et al.
Publicado: (2008)

Anti-IL-6 eluting immunomodulatory biomaterials prolong skin allograft survival
por: Uehara, Mayuko, et al.
Publicado: (2019)

Electrospun, Resorbable, Drug-Eluting, Nanofibrous Membranes Promote Healing of Allograft Tendons
por: Weng, Chun-Jui, et al.
Publicado: (2022)

Abstract: Whole Eye Transplantation: Allograft Survival with Tacrolimus Immunosupression and Comparison to Syngeneic Transplantation
por: Chen, Wendy, et al.
Publicado: (2018)

Comparative effects of hepatocyte growth factor and tacrolimus on acute liver allograft early tolerance
por: Chen, Quanyu, et al.
Publicado: (2023)

Accelerated Cardiac Allograft Vasculopathy in an Orthotopic Heart Transplant Recipient with Prior COVID-19
por: Parikh, Neil U., et al.
Publicado: (2023)

Impact of porcine cytomegalovirus on long-term orthotopic cardiac xenotransplant survival
por: Denner, Joachim, et al.
Publicado: (2020)

Immunological Monitoring of Renal Transplant Recipients to Predict Acute Allograft Rejection Following the Discontinuation of Tacrolimus
por: Kreijveld, Ellen, et al.
Publicado: (2008)

Effects of ASKP1240 Combined With Tacrolimus or Mycophenolate Mofetil on Renal Allograft Survival in Cynomolgus Monkeys
por: Song, Lijun, et al.
Publicado: (2014)

Tacrolimus confers lower acute rejection rates and better renal allograft survival compared to cyclosporine
por: Kamel, Mahmoud, et al.
Publicado: (2016)

Immunomics of Renal Allograft Acute T Cell-Mediated Rejection Biopsies of Tacrolimus- and Belatacept-Treated Patients
por: van der Zwan, Marieke, et al.
Publicado: (2018)

Open-Label, Randomized Study of Transition From Tacrolimus to Sirolimus Immunosuppression in Renal Allograft Recipients
por: Tedesco-Silva, Helio, et al.
Publicado: (2016)

Tacrolimus Blood Level Fluctuation Predisposes to Coexisting BK Virus Nephropathy and Acute Allograft Rejection
por: Shen, Chia-Lin, et al.
Publicado: (2017)

The Impact of Single Nucleotide Polymorphisms on the Pharmacokinetics of Tacrolimus in Kidney Allograft Recipients of Northern-West, Iran
por: Jabbari Hagh, Elaheh, et al.
Publicado: (2023)

Concurrent Hepatic Artery and Portal Vein Thrombosis after Orthotopic Liver Transplantation with Preserved Allografts
por: Khan, Arshad, et al.
Publicado: (2014)

Orthotopic Transplantation of Achilles Tendon Allograft in Rats: With or without Incorporation of Autologous Mesenchymal Stem Cells
por: Aynardi, Michael, et al.
Publicado: (2018)

Alteration of urinary neutrophil gelatinase–associated lipocalin as a predictor of tacrolimus-induced chronic renal allograft fibrosis in tacrolimus dose adjustments following kidney transplantation
por: Chancharoenthana, Wiwat, et al.
Publicado: (2018)

Correction: Alteration of urinary neutrophil gelatinase-associated lipocalin as a predictor of tacrolimus-induced chronic renal allograft fibrosis in tacrolimus dose adjustments following kidney transplantation
Publicado: (2019)

Combined impact of the inter and intra-patient variability of tacrolimus blood level on allograft outcomes in kidney transplantation
por: Park, Yohan, et al.
Publicado: (2022)

Use of drug-coated balloon instead of drug-eluting stent for pediatric cardiac allograft vasculopathy
por: Hirose, Masaki, et al.
Publicado: (2023)

Orthotopic Transplantation of the Full-length Porcine Intestine After Normothermic Machine Perfusion
por: Abraham, Nader, et al.
Publicado: (2022)

Healing of Long-term Frozen Orthotopic Bone Allografts is not Affected by MHC Differences Between Donor and Recipient
por: Reikerås, Olav, et al.
Publicado: (2011)

Diagnostic Accuracy of Dobutamine Stress Echocardiography for Detection of Cardiac Allograft Vasculopathy in Orthotopic Heart Transplant Patients
por: Mahmoodurrahman, Mohammed, et al.
Publicado: (2021)

Procalcitonin in early allograft dysfunction after orthotopic liver transplantation: a retrospective single centre study
por: Frick, Katja, et al.
Publicado: (2022)

Five-year comparative study of thin-strut rapamycin-eluting bioabsorbable scaffold with metallic drug-eluting stent in porcine coronary artery
por: Liu, Yaokun, et al.
Publicado: (2022)

Long-term effect of stents eluting 6-mercaptopurine in porcine coronary arteries
por: Ruiter, Matthijs S., et al.
Publicado: (2016)

Polymer-free dual drug-eluting stents evaluated in a porcine model
por: Zhang, Bin, et al.
Publicado: (2017)

Abstract 37: Whole Eye Allograft Transplantation And Immunosuppression: Survival Of The Transplanted Rodent Eye Using Tacrolimus Monotherapy
por: Chen, Wendy, et al.
Publicado: (2018)

Early Conversion to Tacrolimus Vs Cyclosporine Continuation in Normally Functioning Kidney Allograft: A Single-Center Study
por: Azizzadeh, Laya, et al.
Publicado: (2020)

Everolimus-Eluting Second-Generation Stents for Treatment of De Novo Lesions in Patients with Cardiac Allograft Vasculopathy
por: Pyka, Łukasz, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8vbj9ia5tsoqesuc4jhaav56ms