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Bacterial regulation of macrophage bacterial recognition receptors in COPD are differentially modified by budesonide and fluticasone propionate

RATIONALE: Patients with COPD have an increased risk for community-acquired pneumonia, which is further increased by inhaled corticosteroids. OBJECTIVE: To assess effects of the corticosteroids, budesonide and fluticasone propionate, on macrophage bacterial responses in COPD. METHODS: Monocyte-deriv...

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Detalles Bibliográficos
Autores principales: Provost, Karin A., Smith, Miyuki, Miller-Larsson, Anna, Gudleski, Gregory D., Sethi, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345465/
https://www.ncbi.nlm.nih.gov/pubmed/30677037
http://dx.doi.org/10.1371/journal.pone.0207675