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Vancomycin does not affect the enzymatic activities of purified VanS(A)

VanS is a membrane-bound sensor histidine kinase responsible for sensing vancomycin and activating transcription of vancomycin-resistance genes. In the presence of vancomycin, VanS phosphorylates the transcription factor VanR, converting it to its transcriptionally active form. In the absence of van...

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Detalles Bibliográficos
Autores principales: Upton, Elizabeth C., Maciunas, Lina J., Loll, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345502/
https://www.ncbi.nlm.nih.gov/pubmed/30677074
http://dx.doi.org/10.1371/journal.pone.0210627