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Vancomycin does not affect the enzymatic activities of purified VanS(A)
VanS is a membrane-bound sensor histidine kinase responsible for sensing vancomycin and activating transcription of vancomycin-resistance genes. In the presence of vancomycin, VanS phosphorylates the transcription factor VanR, converting it to its transcriptionally active form. In the absence of van...
Autores principales: | Upton, Elizabeth C., Maciunas, Lina J., Loll, Patrick J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345502/ https://www.ncbi.nlm.nih.gov/pubmed/30677074 http://dx.doi.org/10.1371/journal.pone.0210627 |
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