Cumulative mitochondrial activity correlates with ototoxin susceptibility in zebrafish mechanosensory hair cells

Mitochondria play a prominent role in mechanosensory hair cell damage and death. Although hair cells are thought to be energetically demanding cells, how mitochondria respond to these demands and how this might relate to cell death is largely unexplored. Using genetically encoded indicators, we foun...

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Detalles Bibliográficos
Autores principales: Pickett, Sarah B, Thomas, Eric D, Sebe, Joy Y, Linbo, Tor, Esterberg, Robert, Hailey, Dale W, Raible, David W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345563/
https://www.ncbi.nlm.nih.gov/pubmed/30596476
http://dx.doi.org/10.7554/eLife.38062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345563/
https://www.ncbi.nlm.nih.gov/pubmed/30596476
http://dx.doi.org/10.7554/eLife.38062

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