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Cumulative mitochondrial activity correlates with ototoxin susceptibility in zebrafish mechanosensory hair cells
Mitochondria play a prominent role in mechanosensory hair cell damage and death. Although hair cells are thought to be energetically demanding cells, how mitochondria respond to these demands and how this might relate to cell death is largely unexplored. Using genetically encoded indicators, we foun...
Autores principales: | Pickett, Sarah B, Thomas, Eric D, Sebe, Joy Y, Linbo, Tor, Esterberg, Robert, Hailey, Dale W, Raible, David W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345563/ https://www.ncbi.nlm.nih.gov/pubmed/30596476 http://dx.doi.org/10.7554/eLife.38062 |
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