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Mechanisms of PDZ domain scaffold assembly illuminated by use of supported cell membrane sheets

PDZ domain scaffold proteins are molecular modules orchestrating cellular signalling in space and time. Here, we investigate assembly of PDZ scaffolds using supported cell membrane sheets, a unique experimental setup enabling direct access to the intracellular face of the cell membrane. Our data dem...

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Detalles Bibliográficos
Autores principales: Erlendsson, Simon, Thorsen, Thor Seneca, Vauquelin, Georges, Ammendrup-Johnsen, Ina, Wirth, Volker, Martinez, Karen L, Teilum, Kaare, Gether, Ulrik, Madsen, Kenneth Lindegaard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345565/
https://www.ncbi.nlm.nih.gov/pubmed/30605082
http://dx.doi.org/10.7554/eLife.39180