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Kindlin-1 Regulates Epidermal Growth Factor Receptor Signaling

Kindler syndrome is an autosomal recessive genodermatosis that results from mutations in the FERMT1 gene encoding t kindlin-1. Kindlin-1 localizes to focal adhesion and is known to contribute to the activation of integrin receptors. Most cases of Kindler syndrome show a reduction or complete absence...

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Detalles Bibliográficos
Autores principales: Michael, Magdalene, Begum, Rumena, Chan, Grace K., Whitewood, Austin J., Matthews, Daniel R., Goult, Benjamin T., McGrath, John A., Parsons, Maddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345584/
https://www.ncbi.nlm.nih.gov/pubmed/30248333
http://dx.doi.org/10.1016/j.jid.2018.08.020