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Individual response variations in scaffold-guided bone regeneration are determined by independent strain- and injury-induced mechanisms

This study explored the regenerative osteogenic response in the distal femur of sheep using scaffolds having stiffness values within, and above and below, the range of trabecular bone apparent modulus. Scaffolds 3D-printed from stiff titanium and compliant polyamide were implanted into a cylindrical...

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Detalles Bibliográficos
Autores principales: Reznikov, Natalie, Boughton, Oliver R., Ghouse, Shaaz, Weston, Anne E., Collinson, Lucy, Blunn, Gordon W., Jeffers, Jonathan R.T., Cobb, Justin P., Stevens, Molly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345626/
https://www.ncbi.nlm.nih.gov/pubmed/30611115
http://dx.doi.org/10.1016/j.biomaterials.2018.11.026