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Filopodome Mapping Identifies p130Cas as a Mechanosensitive Regulator of Filopodia Stability

Filopodia are adhesive cellular protrusions specialized in the detection of extracellular matrix (ECM)-derived cues. Although ECM engagement at focal adhesions is known to trigger the recruitment of hundreds of proteins (“adhesome”) to fine-tune cellular behavior, the components of the filopodia adh...

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Detalles Bibliográficos
Autores principales: Jacquemet, Guillaume, Stubb, Aki, Saup, Rafael, Miihkinen, Mitro, Kremneva, Elena, Hamidi, Hellyeh, Ivaska, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345628/
https://www.ncbi.nlm.nih.gov/pubmed/30639111
http://dx.doi.org/10.1016/j.cub.2018.11.053