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Filopodome Mapping Identifies p130Cas as a Mechanosensitive Regulator of Filopodia Stability
Filopodia are adhesive cellular protrusions specialized in the detection of extracellular matrix (ECM)-derived cues. Although ECM engagement at focal adhesions is known to trigger the recruitment of hundreds of proteins (“adhesome”) to fine-tune cellular behavior, the components of the filopodia adh...
Autores principales: | Jacquemet, Guillaume, Stubb, Aki, Saup, Rafael, Miihkinen, Mitro, Kremneva, Elena, Hamidi, Hellyeh, Ivaska, Johanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345628/ https://www.ncbi.nlm.nih.gov/pubmed/30639111 http://dx.doi.org/10.1016/j.cub.2018.11.053 |
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