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Radiation-promoted CDC6 protein stability contributes to radioresistance by regulating senescence and epithelial to mesenchymal transition

Ionizing radiation (IR) is a conventional cancer therapeutic, to which cancer cells develop radioresistance with exposure. The residual cancer cells after radiation treatment also have increased metastatic potential. The mechanisms by which cancer cells develop radioresistance and gain metastatic po...

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Detalles Bibliográficos
Autores principales: Yu, Xiaohui, Liu, Youhong, Yin, Linglong, Peng, Yongbo, Peng, Yuchong, Gao, Yingxue, Yuan, Bowen, Zhu, Qianling, Cao, Tuoyu, Xie, Bowen, Sun, Lunquan, Chen, Yan, Gong, Zhicheng, Qiu, Yuanzheng, Fan, Xuegong, Li, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345673/
https://www.ncbi.nlm.nih.gov/pubmed/30158672
http://dx.doi.org/10.1038/s41388-018-0460-4