Cargando…

TIP60-dependent acetylation of the SPZ1-TWIST complex promotes epithelial–mesenchymal transition and metastasis in liver cancer

Metastasis is the main cause of cancer mortality. However, the triggering mechanisms and regulation of epithelial–mesenchymal transition (EMT) factors in the commitment of metastasis have not been well characterized. Spermatogenic Zip 1 (SPZ1) acts as a proto-oncogene and an upstream regulator of EM...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Li-Ting, Wang, Shen-Nien, Chiou, Shyh-Shin, Liu, Kwei-Yan, Chai, Chee-Yin, Chiang, Cheng-Ming, Huang, Shau-Ku, Yokoyama, Kazunari K., Hsu, Shih-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345675/
https://www.ncbi.nlm.nih.gov/pubmed/30154425
http://dx.doi.org/10.1038/s41388-018-0457-z