Identification of Altered Developmental Pathways in Human Juvenile HD iPSC With 71Q and 109Q Using Transcriptome Profiling

In Huntington disease (HD) subtle symptoms in patients may occur years or even decades prior to diagnosis. HD changes at a molecular level may begin as early as in cells that are non-lineage committed such as stem cells or HD patients induced pluripotent stem cells (iPSCs) offering opportunity to en...

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Detalles Bibliográficos
Autores principales: Świtońska, Karolina, Szlachcic, Wojciech J., Handschuh, Luiza, Wojciechowski, Paweł, Marczak, Łukasz, Stelmaszczuk, Michał, Figlerowicz, Marek, Figiel, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345698/
https://www.ncbi.nlm.nih.gov/pubmed/30713489
http://dx.doi.org/10.3389/fncel.2018.00528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345698/
https://www.ncbi.nlm.nih.gov/pubmed/30713489
http://dx.doi.org/10.3389/fncel.2018.00528

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