Trinucleotide Base Pair Stacking Free Energy for Understanding TF-DNA Recognition and the Functions of SNPs

Single nucleotide polymorphisms (SNPs) affect base pair stacking, which is the primary factor for maintaining the stability of DNA. However, the mechanism of how SNPs lead to phenotype variations is still unclear. In this work, we connected SNPs and base pair stacking by a 3-mer base pair stacking f...

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Detalles Bibliográficos
Autores principales: Li, Gen, Quan, Yuan, Wang, Xiaocong, Liu, Rong, Bie, Lihua, Gao, Jun, Zhang, Hong-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345724/
https://www.ncbi.nlm.nih.gov/pubmed/30713839
http://dx.doi.org/10.3389/fchem.2018.00666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345724/
https://www.ncbi.nlm.nih.gov/pubmed/30713839
http://dx.doi.org/10.3389/fchem.2018.00666

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