Impaired Cu–Zn Superoxide Dismutase (SOD1) and Calcineurin (Cn) Interaction in ALS: A Presumed Consequence for TDP-43 and Zinc Aggregation in Tg SOD1(G93A) Rodent Spinal Cord Tissue

Impaired interactions between Calcineurin (Cn) and (Cu/Zn) superoxide dismutase (SOD1) are suspected to be responsible for the formation of hyperphosphorylated protein aggregation in amyotrophic lateral sclerosis (ALS). Serine (Ser)- enriched phosphorylated TDP-43 protein aggregation appears in the...

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Detalles Bibliográficos
Autores principales: Kim, Jolene M., Billington, Elizabeth, Reyes, Ada, Notarianni, Tara, Sage, Jessica, Agbas, Emre, Taylor, Michael, Monast, Ian, Stanford, John A., Agbas, Abdulbaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345727/
https://www.ncbi.nlm.nih.gov/pubmed/29299811
http://dx.doi.org/10.1007/s11064-017-2461-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345727/
https://www.ncbi.nlm.nih.gov/pubmed/29299811
http://dx.doi.org/10.1007/s11064-017-2461-z

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