Curcumin inhibits the TGF-β1-dependent differentiation of lung fibroblasts via PPARγ-driven upregulation of cathepsins B and L

Pulmonary fibrosis is a progressive disease characterized by a widespread accumulation of myofibroblasts and extracellular matrix components. Growing evidences support that cysteine cathepsins, embracing cathepsin B (CatB) that affects TGF-β1-driven Smad pathway, along with their extracellular inhib...

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Detalles Bibliográficos
Autores principales: Saidi, Ahlame, Kasabova, Mariana, Vanderlynden, Lise, Wartenberg, Mylène, Kara-Ali, Ghania Hounana, Marc, Daniel, Lecaille, Fabien, Lalmanach, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345753/
https://www.ncbi.nlm.nih.gov/pubmed/30679571
http://dx.doi.org/10.1038/s41598-018-36858-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345753/
https://www.ncbi.nlm.nih.gov/pubmed/30679571
http://dx.doi.org/10.1038/s41598-018-36858-3

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