Hypoculoside, a sphingoid base-like compound from Acremonium disrupts the membrane integrity of yeast cells

We have isolated Hypoculoside, a new glycosidic amino alcohol lipid from the fungus Acremonium sp. F2434 belonging to the order Hypocreales and determined its structure by 2D-NMR (Nuclear Magnetic Resonance) spectroscopy. Hypoculoside has antifungal, antibacterial and cytotoxic activities. Homozygou...

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Detalles Bibliográficos
Autores principales: Alfatah, Mohammad, Wong, Jin Huei, Nge, Choy Eng, Kong, Kiat Whye, Low, Kia Ngee, Leong, Chung Yan, Crasta, Sharon, Munusamy, Madhaiyan, Chang, Amanda Mun Leng, Hoon, Shawn, Ng, Siew Bee, Kanagasundaram, Yoganathan, Arumugam, Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345779/
https://www.ncbi.nlm.nih.gov/pubmed/30679518
http://dx.doi.org/10.1038/s41598-018-35979-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345779/
https://www.ncbi.nlm.nih.gov/pubmed/30679518
http://dx.doi.org/10.1038/s41598-018-35979-z

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