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Interactions of HLA-DR and Topoisomerase I Epitope Modulated Genetic Risk for Systemic Sclerosis

The association of systemic sclerosis with anti-Topoisomerase 1 antibody (ATASSc) with specific alleles of human leukocyte antigen (HLA)-DR has been observed among various ethnics. The anti-Topoisomerase 1 antibody is a common autoantibody in SSc with diffuse cutaneous scleroderma, which is one of t...

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Detalles Bibliográficos
Autores principales: Kongkaew, Sirilak, Rungrotmongkol, Thanyada, Punwong, Chutintorn, Noguchi, Hiroshi, Takeuchi, Fujio, Kungwan, Nawee, Wolschann, Peter, Hannongbua, Supot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345791/
https://www.ncbi.nlm.nih.gov/pubmed/30679605
http://dx.doi.org/10.1038/s41598-018-37038-z