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Intrinsic and extrinsic noise of gene expression in lineage trees
Cell-to-cell heterogeneity is driven by stochasticity in intracellular reactions and the population dynamics. While these sources are usually studied separately, we develop an agent-based framework that accounts for both factors while tracking every single cell of a growing population. Apart from th...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345792/ https://www.ncbi.nlm.nih.gov/pubmed/30679440 http://dx.doi.org/10.1038/s41598-018-35927-x |