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ES-mediated chimera analysis revealed requirement of DDX6 for NANOS2 localization and function in mouse germ cells
In embryonic male germ cells, the RNA-binding protein NANOS2 recruits its target RNAs to processing bodies (P-bodies), where they are repressed. This process is necessary to promote male-type germ cell differentiation. However, it remains unclear whether all NANOS2 functions depend on P-bodies. To a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345806/ https://www.ncbi.nlm.nih.gov/pubmed/30679547 http://dx.doi.org/10.1038/s41598-018-36502-0 |