Cargando…

ES-mediated chimera analysis revealed requirement of DDX6 for NANOS2 localization and function in mouse germ cells

In embryonic male germ cells, the RNA-binding protein NANOS2 recruits its target RNAs to processing bodies (P-bodies), where they are repressed. This process is necessary to promote male-type germ cell differentiation. However, it remains unclear whether all NANOS2 functions depend on P-bodies. To a...

Descripción completa

Detalles Bibliográficos
Autores principales: Shimada, Ryuki, Kiso, Makoto, Saga, Yumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345806/
https://www.ncbi.nlm.nih.gov/pubmed/30679547
http://dx.doi.org/10.1038/s41598-018-36502-0