Cargando…
ES-mediated chimera analysis revealed requirement of DDX6 for NANOS2 localization and function in mouse germ cells
In embryonic male germ cells, the RNA-binding protein NANOS2 recruits its target RNAs to processing bodies (P-bodies), where they are repressed. This process is necessary to promote male-type germ cell differentiation. However, it remains unclear whether all NANOS2 functions depend on P-bodies. To a...
Autores principales: | Shimada, Ryuki, Kiso, Makoto, Saga, Yumiko |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345806/ https://www.ncbi.nlm.nih.gov/pubmed/30679547 http://dx.doi.org/10.1038/s41598-018-36502-0 |
Ejemplares similares
-
NANOS2 suppresses the cell cycle by repressing mTORC1 activators in embryonic male germ cells
por: Shimada, Ryuki, et al.
Publicado: (2021) -
The Nanos3-3′UTR Is Required for Germ Cell Specific NANOS3 Expression in Mouse Embryos
por: Suzuki, Hitomi, et al.
Publicado: (2010) -
Interaction of NANOS2 and NANOS3 with different components of the CNOT complex may contribute to the functional differences in mouse male germ cells
por: Suzuki, Atsushi, et al.
Publicado: (2014) -
Interaction between NANOS2 and the CCR4-NOT Deadenylation Complex Is Essential for Male Germ Cell Development in Mouse
por: Suzuki, Atsushi, et al.
Publicado: (2012) -
Generation of Hprt-disrupted rat through mouse←rat ES chimeras
por: Isotani, Ayako, et al.
Publicado: (2016)