HSPA12A targets the cytoplasmic domain and affects the trafficking of the Amyloid Precursor Protein receptor SorLA

SorLA and Sortilin are multifunctional receptors involved in endocytosis and intracellular sorting of different and unrelated ligands. SorLA has recently attracted much attention as a novel strong risk gene for Alzheimer’s disease, and much effort is currently being put into understanding the underl...

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Detalles Bibliográficos
Autores principales: Madsen, Peder, Isaksen, Toke Jost, Siupka, Piotr, Tóth, Andrea E., Nyegaard, Mette, Gustafsen, Camilla, Nielsen, Morten S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345817/
https://www.ncbi.nlm.nih.gov/pubmed/30679749
http://dx.doi.org/10.1038/s41598-018-37336-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345817/
https://www.ncbi.nlm.nih.gov/pubmed/30679749
http://dx.doi.org/10.1038/s41598-018-37336-6

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