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Nebulized hypertonic saline triggers nervous system-mediated active liquid secretion in cystic fibrosis swine trachea

Inhaled hypertonic saline (HTS) treatment is used to improve lung health in patients with cystic fibrosis (CF). The current consensus is that the treatment generates an osmotic gradient that draws water into the airways and increases airway surface liquid (ASL) volume. However, there is evidence tha...

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Detalles Bibliográficos
Autores principales: Luan, Xiaojie, Tam, Julian S., Belev, George, Jagadeeshan, Santosh, Murray, Brendan, Hassan, Noman, Machen, Terry E., Chapman, L. Dean, Ianowski, Juan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345831/
https://www.ncbi.nlm.nih.gov/pubmed/30679487
http://dx.doi.org/10.1038/s41598-018-36695-4