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A high-throughput microscopy method for single-cell analysis of event-time correlations in nanoparticle-induced cell death

The temporal context of cell death decisions remains generally hidden in ensemble measurements with endpoint readouts. Here, we describe a method to extract event times from fluorescence time traces of cell death-related markers in automated live-cell imaging on single-cell arrays (LISCA) using epit...

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Detalles Bibliográficos
Autores principales: Murschhauser, Alexandra, Röttgermann, Peter J. F., Woschée, Daniel, Ober, Martina F., Yan, Yan, Dawson, Kenneth A., Rädler, Joachim O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345847/
https://www.ncbi.nlm.nih.gov/pubmed/30701200
http://dx.doi.org/10.1038/s42003-019-0282-0