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Usp7 regulates Hippo pathway through deubiquitinating the transcriptional coactivator Yorkie

The Hippo pathway plays an important role in organ development and adult tissue homeostasis, and its deregulation has been implicated in many cancers. The Hippo signaling relies on a core kinase cascade culminating in phosphorylation of the transcription coactivator Yorkie (Yki). Although Yki is the...

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Detalles Bibliográficos
Autores principales: Sun, Xiaohan, Ding, Yan, Zhan, Meixiao, Li, Yan, Gao, Dongqing, Wang, Guiping, Gao, Yang, Li, Yong, Wu, Shian, Lu, Ligong, Liu, Qingxin, Zhou, Zizhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345853/
https://www.ncbi.nlm.nih.gov/pubmed/30679505
http://dx.doi.org/10.1038/s41467-019-08334-7