Copper amine oxidases catalyze the oxidative deamination and hydrolysis of cyclic imines

Although cyclic imines are present in various bioactive secondary metabolites, their degradative metabolism remains unknown. Here, we report that copper amine oxidases, which are important in metabolism of primary amines, catalyze a cyclic imine cleavage reaction. We isolate a microorganism (Arthrob...

Descripción completa

Detalles Bibliográficos
Autores principales: Nagakubo, Toshiki, Kumano, Takuto, Ohta, Takehiro, Hashimoto, Yoshiteru, Kobayashi, Michihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345859/
https://www.ncbi.nlm.nih.gov/pubmed/30679427
http://dx.doi.org/10.1038/s41467-018-08280-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345859/
https://www.ncbi.nlm.nih.gov/pubmed/30679427
http://dx.doi.org/10.1038/s41467-018-08280-w

Ejemplares similares