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Copper amine oxidases catalyze the oxidative deamination and hydrolysis of cyclic imines
Although cyclic imines are present in various bioactive secondary metabolites, their degradative metabolism remains unknown. Here, we report that copper amine oxidases, which are important in metabolism of primary amines, catalyze a cyclic imine cleavage reaction. We isolate a microorganism (Arthrob...
Autores principales: | Nagakubo, Toshiki, Kumano, Takuto, Ohta, Takehiro, Hashimoto, Yoshiteru, Kobayashi, Michihiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345859/ https://www.ncbi.nlm.nih.gov/pubmed/30679427 http://dx.doi.org/10.1038/s41467-018-08280-w |
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