TMEM16F activation by Ca(2+) triggers plasma membrane expansion and directs PD-1 trafficking

TMEM16F is a Ca(2+) -gated ion channel that is required for Ca(2+) -activated phosphatidylserine exposure on the surface of many eukaryotic cells. TMEM16F is widely expressed and has roles in platelet activation during blood clotting, bone formation and T cell activation. By combining microscopy and...

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Detalles Bibliográficos
Autores principales: Bricogne, Christopher, Fine, Michael, Pereira, Pedro M., Sung, Julia, Tijani, Maha, Wang, Youxue, Henriques, Ricardo, Collins, Mary K., Hilgemann, Donald W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345885/
https://www.ncbi.nlm.nih.gov/pubmed/30679690
http://dx.doi.org/10.1038/s41598-018-37056-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345885/
https://www.ncbi.nlm.nih.gov/pubmed/30679690
http://dx.doi.org/10.1038/s41598-018-37056-x

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