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Scanning the genomes of parents for imprinted loci acting in their un-genotyped progeny

Depending on their parental origin, alleles at imprinted loci are fully or partially inactivated through epigenetic mechanisms. Their effects contribute to the broader class of parent-of-origin effects. Standard methodology for mapping imprinted quantitative trait loci in association studies require...

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Detalles Bibliográficos
Autores principales: Blunk, Inga, Mayer, Manfred, Hamann, Henning, Reinsch, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345920/
https://www.ncbi.nlm.nih.gov/pubmed/30679576
http://dx.doi.org/10.1038/s41598-018-36939-3