Epitope mapping of anti-PGRMC1 antibodies reveals the non-conventional membrane topology of PGRMC1 on the cell surface

Progesterone receptor membrane component1 (PGRMC1) is a heme-binding protein involved in cancers and Alzheimer’s disease. PGRMC1 consists of a short N-terminal extracellular or luminal domain, a single membrane-spanning domain, and a long cytoplasmic domain. Previously, we generated two monoclonal a...

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Detalles Bibliográficos
Autores principales: Kim, Ji Yea, Kim, So Young, Choi, Hong Seo, An, Sungkwan, Ryu, Chun Jeih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345922/
https://www.ncbi.nlm.nih.gov/pubmed/30679694
http://dx.doi.org/10.1038/s41598-018-37441-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345922/
https://www.ncbi.nlm.nih.gov/pubmed/30679694
http://dx.doi.org/10.1038/s41598-018-37441-6

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