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Chemically defined conditions for long-term maintenance of pancreatic progenitors derived from human induced pluripotent stem cells

Large numbers of hormone-releasing cells, approximately 10(9) endocrine cells, are required to treat type I diabetes patients by cell transplantation. The SOX9-positive pancreatic epithelium proliferates extensively during the early stages of pancreatic development. SOX9-positive pancreatic epitheli...

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Detalles Bibliográficos
Autores principales: Konagaya, Shuhei, Iwata, Hiroo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345937/
https://www.ncbi.nlm.nih.gov/pubmed/30679498
http://dx.doi.org/10.1038/s41598-018-36606-7