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Improving orthotopic mouse models of patient-derived breast cancer brain metastases by a modified intracarotid injection method
Breast cancer brain metastasis (BCBM) remains a major clinical problem. Approximately 10–16% of patients with breast cancer develop brain metastases (BCBM). However, no systemic therapy has gained regulatory approval for the specific treatment of BCBM and this remains an area of persistent, unmet me...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346002/ https://www.ncbi.nlm.nih.gov/pubmed/30679540 http://dx.doi.org/10.1038/s41598-018-36874-3 |