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Epithelial to Mesenchymal transition, eIF2α phosphorylation and Hsp70 expression enable greater tolerance in A549 cells to TiO(2) over ZnO nanoparticles

Type II alveolar cells are highly robust in nature, yet susceptible to aerosolized nanoparticles (NPs). Dysfunction in these specialized cells, can often lead to emphysema, edema, and pulmonary inflammation. Long-time exposure can also lead to dangerous epigenetic modifications and cancer. Among the...

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Detalles Bibliográficos
Autores principales: Martin, Ansie, Sarkar, Angshuman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346025/
https://www.ncbi.nlm.nih.gov/pubmed/30679528
http://dx.doi.org/10.1038/s41598-018-36716-2