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Acidosis Maintains the Function of Brain Mitochondria in Hypoxia-Tolerant Triplefin Fish: A Strategy to Survive Acute Hypoxic Exposure?

The vertebrate brain is generally very sensitive to acidosis, so a hypoxia-induced decrease in pH is likely to have an effect on brain mitochondria (mt). Mitochondrial respiration (JO(2)) is required to generate an electrical gradient (ΔΨm) and a pH gradient to power ATP synthesis, yet the impact of...

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Detalles Bibliográficos
Autores principales: Devaux, Jules B. L., Hedges, Christopher P., Birch, Nigel, Herbert, Neill, Renshaw, Gillian M. C., Hickey, Anthony J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346031/
https://www.ncbi.nlm.nih.gov/pubmed/30713504
http://dx.doi.org/10.3389/fphys.2018.01941