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Acidosis Maintains the Function of Brain Mitochondria in Hypoxia-Tolerant Triplefin Fish: A Strategy to Survive Acute Hypoxic Exposure?
The vertebrate brain is generally very sensitive to acidosis, so a hypoxia-induced decrease in pH is likely to have an effect on brain mitochondria (mt). Mitochondrial respiration (JO(2)) is required to generate an electrical gradient (ΔΨm) and a pH gradient to power ATP synthesis, yet the impact of...
Autores principales: | Devaux, Jules B. L., Hedges, Christopher P., Birch, Nigel, Herbert, Neill, Renshaw, Gillian M. C., Hickey, Anthony J. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346031/ https://www.ncbi.nlm.nih.gov/pubmed/30713504 http://dx.doi.org/10.3389/fphys.2018.01941 |
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