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Drug repositioning for dengue haemorrhagic fever by integrating multiple omics analyses

To detect drug candidates for dengue haemorrhagic fever (DHF), we employed a computational drug repositioning method to perform an integrated multiple omics analysis based on transcriptomic, proteomic, and interactomic data. We identified 3,892 significant genes, 389 proteins, and 221 human proteins...

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Detalles Bibliográficos
Autores principales: Amemiya, Takayuki, Gromiha, M. Michael, Horimoto, Katsuhisa, Fukui, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346040/
https://www.ncbi.nlm.nih.gov/pubmed/30679503
http://dx.doi.org/10.1038/s41598-018-36636-1