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Smoothelin-like 1 deletion enhances myogenic reactivity of mesenteric arteries with alterations in PKC and myosin phosphatase signaling

The role of the smoothelin-like 1 (SMTNL1) protein in mediating vascular smooth muscle contractile responses to intraluminal pressure was examined in resistance vessels. Mesenteric arterioles from wild type (WT) and SMTNL1 global knock-out (KO) mice were examined with pressure myography. SMTNL1 dele...

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Detalles Bibliográficos
Autores principales: Turner, Sara R., Chappellaz, Mona, Popowich, Brittany, Wooldridge, Anne A., Haystead, Timothy A. J., Cole, William C., MacDonald, Justin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346088/
https://www.ncbi.nlm.nih.gov/pubmed/30679490
http://dx.doi.org/10.1038/s41598-018-36564-0