TGF-β-SNAIL axis induces Müller glial-mesenchymal transition in the pathogenesis of idiopathic epiretinal membrane

The epithelial-mesenchymal transition (EMT) is a key process in fibrogenic diseases where transdifferentiated myofibroblasts produce excessive amounts of extracellular matrix, resulting in organ dysfunction. Idiopathic epiretinal membrane (iERM) is a vision-threatening disorder characterized by fibr...

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Detalles Bibliográficos
Autores principales: Kanda, Atsuhiro, Noda, Kousuke, Hirose, Ikuyo, Ishida, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346093/
https://www.ncbi.nlm.nih.gov/pubmed/30679596
http://dx.doi.org/10.1038/s41598-018-36917-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346093/
https://www.ncbi.nlm.nih.gov/pubmed/30679596
http://dx.doi.org/10.1038/s41598-018-36917-9

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