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TGF-β-SNAIL axis induces Müller glial-mesenchymal transition in the pathogenesis of idiopathic epiretinal membrane

The epithelial-mesenchymal transition (EMT) is a key process in fibrogenic diseases where transdifferentiated myofibroblasts produce excessive amounts of extracellular matrix, resulting in organ dysfunction. Idiopathic epiretinal membrane (iERM) is a vision-threatening disorder characterized by fibr...

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Detalles Bibliográficos
Autores principales:	Kanda, Atsuhiro, Noda, Kousuke, Hirose, Ikuyo, Ishida, Susumu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346093/ https://www.ncbi.nlm.nih.gov/pubmed/30679596 http://dx.doi.org/10.1038/s41598-018-36917-9

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