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Prominent action of butyrate over β-hydroxybutyrate as histone deacetylase inhibitor, transcriptional modulator and anti-inflammatory molecule

Butyrate and R-β-hydroxybutyrate are two related short chain fatty acids naturally found in mammals. Butyrate, produced by enteric butyric bacteria, is present at millimolar concentrations in the gastrointestinal tract and at lower levels in blood; R-β-hydroxybutyrate, the main ketone body, produced...

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Detalles Bibliográficos
Autores principales: Chriett, Sabrina, Dąbek, Arkadiusz, Wojtala, Martyna, Vidal, Hubert, Balcerczyk, Aneta, Pirola, Luciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346118/
https://www.ncbi.nlm.nih.gov/pubmed/30679586
http://dx.doi.org/10.1038/s41598-018-36941-9