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Prominent action of butyrate over β-hydroxybutyrate as histone deacetylase inhibitor, transcriptional modulator and anti-inflammatory molecule
Butyrate and R-β-hydroxybutyrate are two related short chain fatty acids naturally found in mammals. Butyrate, produced by enteric butyric bacteria, is present at millimolar concentrations in the gastrointestinal tract and at lower levels in blood; R-β-hydroxybutyrate, the main ketone body, produced...
Autores principales: | Chriett, Sabrina, Dąbek, Arkadiusz, Wojtala, Martyna, Vidal, Hubert, Balcerczyk, Aneta, Pirola, Luciano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346118/ https://www.ncbi.nlm.nih.gov/pubmed/30679586 http://dx.doi.org/10.1038/s41598-018-36941-9 |
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