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Up-regulation of activation-induced cytidine deaminase and its strong expression in extra-germinal centres in IgG4-related disease

Immunoglobulin (Ig) G4-related disease (IgG4-RD) is a systemic disorder involving benign mass formation due to fibrosis and intense lymphoplasmacytosis; the chronic inflammation associated with the disease might also contribute to oncogenesis. Activation-induced cytidine deaminase (AID), normally ex...

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Detalles Bibliográficos
Autores principales: Gion, Yuka, Takeuchi, Mai, Shibata, Rei, Takata, Katsuyoshi, Miyata-Takata, Tomoko, Orita, Yorihisa, Tachibana, Tomoyasu, Yoshino, Tadashi, Sato, Yasuharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346144/
https://www.ncbi.nlm.nih.gov/pubmed/30679751
http://dx.doi.org/10.1038/s41598-018-37404-x