An integrated transcriptome analysis in T‐cell acute lymphoblastic leukemia links DNA methylation subgroups to dysregulated TAL1 and ANTP homeobox gene expression

Classification of pediatric T‐cell acute lymphoblastic leukemia (T‐ALL) patients into CIMP (CpG Island Methylator Phenotype) subgroups has the potential to improve current risk stratification. To investigate the biology behind these CIMP subgroups, diagnostic samples from Nordic pediatric T‐ALL pati...

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Detalles Bibliográficos
Autores principales: Haider, Zahra, Larsson, Pär, Landfors, Mattias, Köhn, Linda, Schmiegelow, Kjeld, Flægstad, Trond, Kanerva, Jukka, Heyman, Mats, Hultdin, Magnus, Degerman, Sofie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346238/
https://www.ncbi.nlm.nih.gov/pubmed/30575306
http://dx.doi.org/10.1002/cam4.1917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346238/
https://www.ncbi.nlm.nih.gov/pubmed/30575306
http://dx.doi.org/10.1002/cam4.1917

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