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Syntheses of defined sulfated oligohyaluronans reveal structural effects, diversity and thermodynamics of GAG–protein binding

Binding of sulfated glycosaminoglycans (GAG) to a wide spectrum of extracellular regulatory proteins is crucial for physiological processes such as cell growth, migration, tissue homeostasis and repair. Thus, GAG derivatives exhibit great relevance in the development of innovative biomaterials for t...

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Detalles Bibliográficos
Autores principales: Köhling, Sebastian, Blaszkiewicz, Joanna, Ruiz-Gómez, Gloria, Fernández-Bachiller, María Isabel, Lemmnitzer, Katharina, Panitz, Nydia, Beck-Sickinger, Annette G., Schiller, Jürgen, Pisabarro, M. Teresa, Rademann, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346292/
https://www.ncbi.nlm.nih.gov/pubmed/30774881
http://dx.doi.org/10.1039/c8sc03649g